CCT7 Antikörper (N-Term)

Produktnummer ABIN1881183

Dieses Anti-CCT7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CCT7 in WB. Geeignet für Human. Dieses Primary Antibody wurde in 5+ Publikationen zitiert.

Kurzübersicht für CCT7 Antikörper (N-Term) (ABIN1881183)

Target: CCT7 (Chaperonin Containing TCP1, Subunit 7 (Eta) (CCT7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB42785

Produktdetails anti-CCT7 Antikörper

Bindungsspezifität: AA 64-92, N-Term

Homologie: B, C, M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CCT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the N-terminal region of human CCT7.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-CCT7 Antikörper (ABIN1881183)

Mukherjee, Conway de Macario, Macario, Brocchieri: "Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes." in: BMC evolutionary biology, Vol. 10, pp. 64, (2010) (PubMed).

Zebol, Hewitt, Moretti, Lynn, Lake, Li, Vadas, Wattenberg, Pitson: "The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1." in: The international journal of biochemistry & cell biology, Vol. 41, Issue 4, pp. 822-7, (2009) (PubMed).

Guo, Han, Adam, Colburn, Wang, Dong, Eizirik, She, Wang: "Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress." in: Biochemical and biophysical research communications, Vol. 337, Issue 4, pp. 1308-18, (2005) (PubMed).

Hanafy, Martin, Murad: "CCTeta, a novel soluble guanylyl cyclase-interacting protein." in: The Journal of biological chemistry, Vol. 279, Issue 45, pp. 46946-53, (2004) (PubMed).

Imai, Soda, Murakami, Shoji, Abe, Takahashi: "A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death." in: The Journal of biological chemistry, Vol. 278, Issue 51, pp. 51901-10, (2003) (PubMed).

Details zu CCT7

Target: CCT7 (Chaperonin Containing TCP1, Subunit 7 (Eta) (CCT7))

Andere Bezeichnung: CCT7

Hintergrund: This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.

Molekulargewicht: 59367

NCBI Accession: NP_001009570, NP_001159756, NP_001159757, NP_006420

UniProt: Q99832