CNR1 Antikörper (AA 161-187)

Produktnummer ABIN1881140

Der Kaninchen Polyklonal Anti-CNR1-Antikörper wurde für WB validiert. Er ist geeignet, CNR1 in Proben von Human zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für CNR1 Antikörper (AA 161-187) (ABIN1881140)

Target: CNR1 (Cannabinoid Receptor 1 (CNR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB41743

Produktdetails anti-CNR1 Antikörper

Bindungsspezifität: AA 161-187

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-187 amino acids of human CB1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-CNR1 Antikörper (ABIN1881140)

Van Laere, Casteels, Dhollander, Goffin, Grachev, Bormans, Vandenberghe: "Widespread decrease of type 1 cannabinoid receptor availability in Huntington disease in vivo." in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 51, Issue 9, pp. 1413-7, (2010) (PubMed).

Monteleone, Milano, Petrella, Canestrelli, Maj: "Endocannabinoid Pro129Thr FAAH functional polymorphism but not 1359G/A CNR1 polymorphism is associated with antipsychotic-induced weight gain." in: Journal of clinical psychopharmacology, Vol. 30, Issue 4, pp. 441-5, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Larrinaga, Varona, Pérez, Sanz, Ugalde, Cándenas, Pinto, Gil, López: "Expression of cannabinoid receptors in human kidney." in: Histology and histopathology, Vol. 25, Issue 9, pp. 1133-8, (2010) (PubMed).

Details zu CNR1

Target: CNR1 (Cannabinoid Receptor 1 (CNR1))

Andere Bezeichnung: CB1

Hintergrund: This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq].

Molekulargewicht: 52858

NCBI Accession: NP_001153698, NP_001153730, NP_001153731, NP_057167, NP_149421

UniProt: P21554

Pathways: Feeding Behaviour