BRSK1 Antikörper (AA 355-384)

Produktnummer ABIN1881121

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BRSK1 in WB. Er zeigt eine Reaktivität gegenüber Maus und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für BRSK1 Antikörper (AA 355-384) (ABIN1881121)

Target: BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRSK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB40234

Produktdetails anti-BRSK1 Antikörper

Bindungsspezifität: AA 355-384

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BRSK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 355-384 amino acids from the Central region of human BRSK1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-BRSK1 Antikörper (ABIN1881121)

Alvarado-Kristensson, Rodríguez, Silió, Valpuesta, Carrera: "SADB phosphorylation of gamma-tubulin regulates centrosome duplication." in: Nature cell biology, Vol. 11, Issue 9, pp. 1081-92, (2009) (PubMed).

Fogarty, Hardie: "C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest." in: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 77-84, (2008) (PubMed).

Bright, Carling, Thornton: "Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation." in: The Journal of biological chemistry, Vol. 283, Issue 22, pp. 14946-54, (2008) (PubMed).

Details zu BRSK1

Target: BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

Andere Bezeichnung: BRSK1

Hintergrund: Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV-or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.

Molekulargewicht: 85087

NCBI Accession: NP_115806

UniProt: Q8TDC3