BLMH Antikörper (AA 212-242)
Kurzübersicht für BLMH Antikörper (AA 212-242) (ABIN1881113)
Target
Alle BLMH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 212-242
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Homologie
- Rb
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This BLMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-242 amino acids from the Central region of human BLMH.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:25
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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: "Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance." in: Cancer research, Vol. 56, Issue 8, pp. 1746-50, (1996) (PubMed).
: "Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization." in: Biochemistry, Vol. 35, Issue 21, pp. 6706-14, (1996) (PubMed).
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: "Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance." in: Cancer research, Vol. 56, Issue 8, pp. 1746-50, (1996) (PubMed).
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- BLMH (Bleomycin Hydrolase (BLMH))
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Andere Bezeichnung
- BLMH
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Hintergrund
- The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity).
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Molekulargewicht
- 52562
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NCBI Accession
- NP_000377
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UniProt
- Q13867
Target
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