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CD51/CD61 Antikörper

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD51/CD61 in FACS, IP und IHC (fro). Er zeigt eine Reaktivität gegenüber Human und Huhn.
Produktnummer ABIN187672

Kurzübersicht für CD51/CD61 Antikörper (ABIN187672)

Target

Alle CD51/CD61 (ITGAV/ITGB3) Antikörper anzeigen
CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Reaktivität

  • 35
  • 19
  • 19
  • 9
  • 6
  • 5
  • 5
  • 5
  • 5
  • 2
Human, Huhn

Wirt

  • 19
  • 16
Maus

Klonalität

  • 19
  • 16
Monoklonal

Konjugat

  • 7
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD51/CD61 Antikörper ist unkonjugiert

Applikation

  • 29
  • 21
  • 13
  • 13
  • 11
  • 8
  • 6
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon

23C6
  • Spezifität

    Recognizes 110/90 kDa antigen known as the alpha chain of the vitronectin receptor (VNR). Clone 23C6 reacts with osteoclasts, placenta, melanoma cell lines, some epithelia cells. It reacts weakly with platelets. Clone 23C6 recognises the intact complex formed between the CD51 and CD61 molecules (av and b3 integrins). This complex binds vitronectin at the RGD sequence and can also bind von Willebrand factor, fibrinogen, thrombospondin, fibronectin, osteopontin and collagen. Species Reactivity: Human and chicken. Does not cross react with porcine, lapine or bovine tissues.

    Immunogen

    Human osteoclastoma tissue

    Isotyp

    IgG1
  • Applikationshinweise

    Flow Cytometry: Working dilution of 1:40 -1:80. Recommended second antibodies: FITC-conjugated F(ab')2 rabbit anti-mouse IgG Immunohistochemistry -Frozen sections: Working dilution of 1:50-1:100. Clone 23C6 shows no reactivity on fixed tissues. Immunoprecipitation The optimal dilution for a specific application should be determined by the researcher.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Product: 200 µg purified IgG at approximately 1 mg/mL in PBS at pH 7.4 with 0.09% sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C
  • Target

    CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

    Andere Bezeichnung

    CD51/CD61 Complex
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