MVP Antikörper

Produktnummer ABIN187371

Der Maus Monoklonal anti-MVP Antikörper (Klon 5J2) (ABIN187371) detektiert spezifisch MVP in WB und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MVP Antikörper (ABIN187371)

Target: MVP (Major Vault Protein (MVP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MVP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 5J2

Produktdetails anti-MVP Antikörper

Spezifität: The mAb 1011 is specific for a 104 kDa protein. This mAb is one of four mAb which recognize different epitopes of the protein. This 104 kDa protein is the major vault protein and has shown to interact with the estrogen receptor. The protein is part of a very large vault ribonucleoprotein complex present in all eukaryotic cells and its structure and protein composition is highly conserved. Because of the size, shape, and protein and RNA composition of this complex the particles are different from other ribonucleoproteins. Species Reactivity: Human, others not tested.

Immunogen: Recombinant human MVPA BALB/c mouse was immunized with 5 µg of affinity purified nuclear extract proteins. Spleen cells were fused with equal number of Sp0Ag-14 myeloma cells. Cells whose supernatant showed a positive signal for a 104 kDa band were selected and cloned by limited dilution.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The mAb 1011 can be applied for the detection of the major vault protein in a large number of eukaryotic cells including the MCF-7 and Hela tumor cell lines. The mAb are especially applicable to study the association of estrogen receptor with vaults and the study of the mechanism of action of estrogenic hormones. Western blot Immunohistology (Frozen) The optimal dilution for a specific application should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 100 µg purified antibody.

Lagerung: 4 °C

Details zu MVP

Target: MVP (Major Vault Protein (MVP))

Andere Bezeichnung: Major Vault Protein