Aggrecan Antikörper (AA 588-684)

Produktnummer ABIN1857938

Der Kaninchen Polyklonal Anti-Aggrecan-Antikörper wurde für WB, IHC, IP und ICC validiert. Er ist geeignet, Aggrecan in Proben von Ratte zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Aggrecan Antikörper (AA 588-684) (ABIN1857938)

Target: Aggrecan (ACAN)

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aggrecan Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Produktdetails anti-Aggrecan Antikörper

Bindungsspezifität: AA 588-684

Verwendungszweck: Polyclonal Antibody to Aggrecan (AGC)

Spezifität: The antibody is a rabbit polyclonal antibody raised against AGC. It has been selected for its ability to recognize AGC in immunohistochemical staining and western blotting.

Kreuzreaktivität: Human

Aufreinigung: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: RPB908Ra02Recombinant Aggrecan (AGC)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Kommentare:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.3 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Aggrecan Antikörper (ABIN1857938)

Chu, Dai, Wang, Tian, Song, Xiao, Shao, Zhang, Zhang: "Strontium ranelate causes osteophytes overgrowth in a model of early phase osteoarthritis." in: BMC musculoskeletal disorders, Vol. 18, Issue 1, pp. 78, (2017) (PubMed).

Dai, Chu, Tian, Song, Wang, Zhang, Zhang: "Parathyroid hormone(1-34) exhibits more comprehensive effects than celecoxib in cartilage metabolism and maintaining subchondral bone micro-architecture in meniscectomized guinea pigs." in: Osteoarthritis and cartilage, Vol. 24, Issue 6, pp. 1103-12, (2016) (PubMed).

Details zu Aggrecan

Target: Aggrecan (ACAN)

Andere Bezeichnung: Aggrecan

Hintergrund: ACAN, AGC1, AGCAN, CSPG1, CSPCP, CSPGCP, MSK16, SEDK, Cartilage-specific proteoglycan core protein, Large Aggregating Proteoglycan, Chondroitin Sulfate Proteoglycan 1

Pathways: Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport