AIRE Antikörper (Internal Region)
Kurzübersicht für AIRE Antikörper (Internal Region) (ABIN185643)
Target
Alle AIRE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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    - 
                                            Bindungsspezifität
- Internal Region
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                                            Verwendungszweck
- AIRE
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                                            Sequenz
- KDVDLSQPRK GRKP
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                                            Kreuzreaktivität
- Rind (Kuh), Hund, Human, Ratte
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                                            Aufreinigung
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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                                            Immunogen
- Peptide with sequence C-KDVDLSQPRKGRKP, from the internal region of the protein sequence according to NP_000374.1.
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                                            Isotyp
- IgG
 
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                                            Applikationshinweise
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                        Immunohistochemistry: In paraffin embedded Human Thymus shows nuclear staining in select thymocytes. This antibody has been successfully used in IHC on Human: Ströbel P et al. (2014) PMID: 24236644. This antibody has been successfully used in IHC on Pig: Western Blot: Appr. 60 kDa in transfected HEK293 lysates (calculated MW of 57.7 kDa according to NP_000374.1). Recommended concentration: 0.5-1.0 μg/mL. Peptide ELISA: antibody detection limit dilution 1:32000. 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Konzentration
- 0.5 mg/mL
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                                            Buffer
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Handhabung
- Minimize freezing and thawing.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
 
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    - 
                                            : "Transcriptional and histological analyses of the thymic developmental process in the fetal pig."    in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 63, Issue 2, pp. 215-25, (2014)         (PubMed).        
 : "Corticomedullary differentiation and maturational arrest in thymomas." in: Histopathology, Vol. 64, Issue 4, pp. 557-66, (2014) (PubMed).
 
 
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                                            : "Transcriptional and histological analyses of the thymic developmental process in the fetal pig."    in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 63, Issue 2, pp. 215-25, (2014)         (PubMed).        
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    - AIRE (Autoimmune Regulator (AIRE))
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                                            Andere Bezeichnung
- AIRE
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                                            Hintergrund
- AIRE, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) , AIRE1, APECED, APS1, APSI, PGA1 , autoimmune regulator (APECED protein), autoimmune regulator (automimmune polyendocrinopathy candidiasis ectodermal dystrophy),
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                                            Gen-ID
- 326
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                                            NCBI Accession
- NP_000374
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                                            Pathways
- Chromatin Binding
 Target
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