KEAP1 Antikörper (AA 380-624)
Kurzübersicht für KEAP1 Antikörper (AA 380-624) (ABIN1846111)
Target
Alle KEAP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 380-624
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human KEAP1 (AA: 380-624) expressed in E. coli.
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
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Andere Bezeichnung
- KEAP1
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Hintergrund
- This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain.Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus.This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
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Molekulargewicht
- 69.7 kDa
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Gen-ID
- 9817
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UniProt
- Q14145
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Pathways
- Maintenance of Protein Location
Target
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