EGFR Mutant (AA 693-893), (Mutant) Antikörper

Produktnummer ABIN1845729

Produktdetails

Target: EGFR Mutant

Bindungsspezifität: AA 693-893, Mutant

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Applikation: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human EGFR mutant (AA: 693-893) expressed in E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Antigendetails

Target: EGFR Mutant

Hintergrund: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily.This protein is a receptor for members of the epidermal growth factor family.EGFR is a cell surface protein that binds to epidermal growth factor.Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation.Mutations in this gene are associated with lung cancer.Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Molekulargewicht: 175 kDa

Gen-ID: 1956

UniProt: P00533