TIAM1 Antikörper (N-Term)

Produktnummer ABIN1841841

Dieses Anti-TIAM1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TIAM1 in WB und IHC. Geeignet für Human.

Kurzübersicht für TIAM1 Antikörper (N-Term) (ABIN1841841)

Target: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIAM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TIAM1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Rabbit antibody to TIAM 1

Spezifität: Specific for TIAM1.

Kreuzreaktivität: Human, Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic peptide from n-terminal region of human T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 TIAM1) conjugated to an immunogenic carrier protein was used as the antigen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu TIAM1

Target: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Andere Bezeichnung: TIAM 1

Hintergrund: FUNCTION: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1 CDC42 and to a lesser extent RHOA. SUBUNIT: Interacts with BAIAP2. TISSUE SPECIFICITY: Found in virtually all analyzed tumor cell lines including B- and T-lymphomas neuroblastomas melanomas and carcinomas.

UniProt: Q13009