Asialoglycoprotein Receptor 1 Antikörper

Produktnummer ABIN1839609

Dieses Anti-Asialoglycoprotein Receptor 1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Asialoglycoprotein Receptor 1 in WB, IHC, IHC (fro) und FACS. Geeignet für Human.

Kurzübersicht für Asialoglycoprotein Receptor 1 Antikörper (ABIN1839609)

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Asialoglycoprotein Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

Klon: 8D7

Produktdetails anti-Asialoglycoprotein Receptor 1 Antikörper

Spezifität: The asialoglycoprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kD) which mediates binding, internalization and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i. e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediates the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed.

Aufreinigung: Purified

Immunogen: Crude rat liver membrane extracts.

Type of Immunogen: Membrane extract

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo, IHC, IHC-Fr, WB

Usage: For use in Western blot, non-reducing conditions are required.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.02 % sodium azide, 0.1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Details zu Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Andere Bezeichnung: ASGR1 / ASGPR

Hintergrund: Name/Gene ID: ASGR1

Synonyms: ASGR1, ASGPR1, ASGPR, ASGPR 1, Asialoglycoprotein receptor 1, Hepatic lectin H1, HL-1, ASGP-R 1, CLEC4H1

Gen-ID: 432

UniProt: P07306

Pathways: Thyroid Hormone Synthesis