CD177 Antikörper
Kurzübersicht für CD177 Antikörper (ABIN1837719)
Target
Alle CD177 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Cd177 (NP1), a glycosyl phosphatidylinositol (GPI) linked N glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia and analyses showed cell surface expression of a 60 kD protein, 14 kD greater than the predicted size, probably due to the presence of 3 potential N glycosylation sites. Immunohistochemistry demonstrated expression in bone marrow early erythroblasts, megakaryocytes, promyelocytes, and myelocytes. The neutrophil NB1 antigen (CD177) is expressed by 97 % of the Caucasian population. Antibodies against NB1 can be involved in neonatal alloimmune neutropenia (NAN).
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Aufreinigung
- Purified
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Immunogen
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Human granulocytes.
Type of Immunogen: Cells -
Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 4°C.
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- CD177 (CD177 Molecule (CD177))
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Andere Bezeichnung
- CD177
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Hintergrund
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Name/Gene ID: CD177
Synonyms: CD177, CD177 Molecule, CD177 antigen, Cell surface receptor, HNA-2a, HNA2A, NB1, PRV-1, Polycythemia rubra vera 1, PRV1, NB1 glycoprotein, NB1 GP -
Gen-ID
- 57126
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UniProt
- Q8N6Q3
Target
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