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Aggrecan Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Aggrecan in WB, IHC, IP, ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human und Rind (Kuh).
Produktnummer ABIN1834915

Kurzübersicht für Aggrecan Antikörper (ABIN1834915)

Target

Alle Aggrecan (ACAN) Antikörper anzeigen
Aggrecan (ACAN)

Reaktivität

  • 90
  • 48
  • 34
  • 19
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Rind (Kuh)

Wirt

  • 91
  • 25
  • 1
  • 1
Maus

Klonalität

  • 84
  • 34
Monoklonal

Konjugat

  • 65
  • 15
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Aggrecan Antikörper ist unkonjugiert

Applikation

  • 87
  • 56
  • 38
  • 31
  • 22
  • 14
  • 14
  • 12
  • 8
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon

7D4
  • Spezifität

    Recognizes human aggrecan, a proteoglycan and member of the aggrecan/versican proteoglycan family, which forms a major component of the extracellular matrix (ECM) of both cartilage and the central nervous system (CNS). Studies using a panel of core protein-directed antibodies against human aggrecan, revealed the distribution of different aggrecan isoforms within the CNS, and sub-divided the isoforms into clusters 1-5 accordingly. These studies also showed a difference in the relative abundance of these isoforms when comparing brain and cartilage tissues. recognizes epitopes within the N-terminal G1-IGD-G2 region of aggrecan, that has been identified as a cluster 1 isoform.

    Keine Kreuzreaktivität

    Fisch, Huhn, Ratte (Rattus)

    Aufreinigung

    Protein G purified

    Immunogen

    Purified human articular cartilage aggrecan.

    Isotyp

    IgG1
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Kommentare

    Target Species of Antibody: Human

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    PBS, 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    4°C or -20°C, Avoid freeze-thaw cycles.
  • Target

    Aggrecan (ACAN)

    Andere Bezeichnung

    Aggrecan

    Hintergrund

    Name/Gene ID: ACAN

    Synonyms: ACAN, AGCAN, Aggrecan core protein, Acg1, Aggrecan, CSPG1, CSPGCP, CSPCP, AGC1, Aggrecan 1, Large aggregating proteoglycan, MSK16, SEDK, MCSPG

    Gen-ID

    176

    Pathways

    Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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