NEFH Antikörper
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- Target Alle NEFH Antikörper anzeigen
- NEFH (Neurofilament, Heavy Polypeptide (NEFH))
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Reaktivität
- Human, Ratte, Maus, Rind (Kuh)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NEFH Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- Recognizes bovine intermediate 200 kD Neurofilament H (NFH), a 1026 amino acid ~200 kD protein involved in the maintenance of neuronal integrity. Neurofilaments are a major component of the cellular cytoskeleton, acting as the most abundant support for the axon cytoplasm. They exist as three neurofilament proteins: 68/70 kD (NFL) 160 kD (NFM) and 200 kD (NFH), which are expressed in both the central and peripheral nervous systems. Although typically expressed by neurons, neurofilaments are also expressed by neuroblastomas, neuromas, gangliogliomas, ganglioneuromas, and ganglioneuroblastomas, as well as paragangliomas, carcinoids, skin neuroendocrine carcinomas, and oat cell carcinomas of the lung. Defects in NFH are responsible for susceptibility to the neurodegenerative disorder amyotrophic lateral sclerosis (ALS) which affects upper and lower motor neurons, and results in fatal paralysis.
- Aufreinigung
- Purified
- Immunogen
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GST-tagged bovine NFH recombinant protein.
Type of Immunogen: Recombinant protein - Isotyp
- IgG
- Top Product
- Discover our top product NEFH Primärantikörper
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- Applikationshinweise
- Approved: IHC, IHC-P (1 μg/mL), WB (0.1 μg/mL)
- Kommentare
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Target Species of Antibody: Bovine
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Tris-glycine buffered saline, sodium chloride, 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- NEFH (Neurofilament, Heavy Polypeptide (NEFH))
- Andere Bezeichnung
- NEFH / NF-H (NEFH Produkte)
- Synonyme
- NF-H antikoerper, NF200 antikoerper, Nfh antikoerper, mKIAA0845 antikoerper, NFH antikoerper, NEFH antikoerper, neurofilament heavy polypeptide antikoerper, neurofilament, heavy polypeptide antikoerper, neurofilament heavy antikoerper, MCYG_06231 antikoerper, Nefh antikoerper, NEFH antikoerper
- Hintergrund
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Name/Gene ID: NEFH
Synonyms: NEFH, 200 kDa neurofilament protein, KIAA0845, NFH, NF-H - Gen-ID
- 4744
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