NEFH Antikörper

Produktnummer ABIN1834898

Der Kaninchen Polyklonal Anti-NEFH-Antikörper wurde für WB, IHC und IHC (p) validiert. Er ist geeignet, NEFH in Proben von Human, Ratte, Maus und Rind (Kuh) zu detektieren.

Kurzübersicht für NEFH Antikörper (ABIN1834898)

Target: NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Reaktivität: Human, Ratte, Maus, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEFH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NEFH Antikörper

Spezifität: Recognizes bovine intermediate 200 kD Neurofilament H (NFH), a 1026 amino acid ~200 kD protein involved in the maintenance of neuronal integrity. Neurofilaments are a major component of the cellular cytoskeleton, acting as the most abundant support for the axon cytoplasm. They exist as three neurofilament proteins: 68/70 kD (NFL) 160 kD (NFM) and 200 kD (NFH), which are expressed in both the central and peripheral nervous systems. Although typically expressed by neurons, neurofilaments are also expressed by neuroblastomas, neuromas, gangliogliomas, ganglioneuromas, and ganglioneuroblastomas, as well as paragangliomas, carcinoids, skin neuroendocrine carcinomas, and oat cell carcinomas of the lung. Defects in NFH are responsible for susceptibility to the neurodegenerative disorder amyotrophic lateral sclerosis (ALS) which affects upper and lower motor neurons, and results in fatal paralysis.

Aufreinigung: Purified

Immunogen: GST-tagged bovine NFH recombinant protein.

Type of Immunogen: Recombinant protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (1 μg/mL), WB (0.1 μg/mL)

Kommentare:

Target Species of Antibody: Bovine

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-glycine buffered saline, sodium chloride, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu NEFH

Target: NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Andere Bezeichnung: NEFH / NF-H

Hintergrund: Name/Gene ID: NEFH

Synonyms: NEFH, 200 kDa neurofilament protein, KIAA0845, NFH, NF-H

Gen-ID: 4744