Factor VIII Antikörper
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- Target Alle Factor VIII (F8) Antikörper anzeigen
- Factor VIII (F8) (Coagulation Factor VIII (F8))
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Reaktivität
- Human, Schwein
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Factor VIII Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Radioimmunoassay (RIA)
- Spezifität
- Recognizes human Factor VIII, an essential blood coagulation factor. Whilst circulating in the blood, it is mostly stably complexed to von Willebrand factor. It is activated through cleavage at various sites, dissociates from the complex and interacts with Factor IXa, in the presence of calcium ions and phospholipids, to convert Factor X to the activated Factor Xa, which activates thrombin. Thrombin cleaves fibrinogen into fibrin, which polymerises and cross-links to form a blood clot. The activated Factor VIII is proteolytically inactivated and cleared from the bloodstream. Defects in Factor VIII cause hemophilia A, a disorder characterized by the body's inability to control blood clotting. This could result in severe blood loss, even with minor injuries. Clone RFF-VIIIC/8 is a very potent coagulation inhibitor. It recognizes an epitope towards the N-terminus of full-length Factor VIII. It also recognizes the 210kD, 90kD and 40kD cleavage products. This clone does not cross-react with von Willebrand factor.
- Keine Kreuzreaktivität
- Maus, Hund, Ratte (Rattus)
- Aufreinigung
- Protein G purified
- Immunogen
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Affinity purified human Factor VIII.
Type of Immunogen: Purified protein - Klon
- RFF-VIIIC-8
- Isotyp
- IgG1
- Top Product
- Discover our top product F8 Primärantikörper
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- Applikationshinweise
- Approved: ELISA (1:500 - 1:15000), RIA, WB
- Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- Factor VIII (F8) (Coagulation Factor VIII (F8))
- Andere Bezeichnung
- F8 / FVIII / Factor VIII (F8 Produkte)
- Synonyme
- fb61d02 antikoerper, wu:fb61d02 antikoerper, Cf-8 antikoerper, Cf8 antikoerper, FVIII antikoerper, AHF antikoerper, DXS1253E antikoerper, F8B antikoerper, F8C antikoerper, HEMA antikoerper, coagulation factor VIIi antikoerper, coagulation factor VIII antikoerper, coagulation factor VIII, procoagulant component antikoerper, f7i antikoerper, F8 antikoerper
- Hintergrund
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Name/Gene ID: F8
Synonyms: F8, AHF, Antihemophilic factor, Coagulation factor VIIIc, Coagulation factor VIII, DXS1253E, Factor VIII F8B, FVIII, HEMA, F8B, Factor VIII, Procoagulant component, F8C - Gen-ID
- 2157
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