TREM1 Antikörper

Produktnummer ABIN1819860

Produktdetails anti-TREM1 Antikörper

Target: TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser TREM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Spezifität: Recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection.

Aufreinigung: Protein G purified

Immunogen: Mouse TREM-1 Fc fusion protein.
Immunogen type: Fusion protein

Klon: L5-B8-2A12-3A12

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flo (1:25 - 1:100), IF, IHC-Fr, WB

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Details zu TREM1

Target: TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

Andere Bezeichnung: TREM1 / TREM-1 (TREM1 Produkte)

Synonyme: TREM1 antikoerper, CD354 antikoerper, TREM-1 antikoerper, triggering receptor expressed on myeloid cells 1 antikoerper, TREM1 antikoerper, Trem1 antikoerper, LOC100349504 antikoerper

Hintergrund: Synonyms :
TREM1, CD354, CD354 antigen, Triggering-receptor TREM1, TREM-1

Gen-ID: 54210

UniProt: Q9NP99