TREM1 Antikörper

Produktnummer ABIN1819858

Produktdetails anti-TREM1 Antikörper

Target: TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser TREM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Functional Studies (Func)

Spezifität: Recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection.

Aufreinigung: Protein G purified

Immunogen: Mouse TREM-1 Fc fusion protein.
ImmunogenType: Fusion protein

Klon: L5-B8-2A12-3A12

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flo (1:25 - 1:100) IF, IHC-Fr

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.

Details zu TREM1

Target: TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

Andere Bezeichnung: TREM1 (TREM1 Produkte)

Hintergrund: Synonyms :
TREM1, CD354, CD354 antigen, Triggering-receptor TREM1, TREM-1

Gen-ID: 54210