P-Selectin Antikörper (PE)

Produktnummer ABIN181983

Produktdetails anti-P-Selectin Antikörper (PE)

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reaktivität: Human, Maus, Ratte, Schaf, Rind (Kuh), Ziege, Cat, Pferd

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser P-Selectin Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: This antibody recognises the CD62P cell surface antigen, a 140 kDa glycoprotein also known as P-Selectin.

Produktmerkmale: Absorption / Emission: 488nm / 575nm

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: P-selectin transfected 300.19 cells.

Klon: Psel-KO-2-7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Use 10 μL of Neat-1/5 diluted antibody to label 106 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1.0 mL distilled water

Konzentration: approx. 0.1 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA, 5 % Sucrose

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: This product is photosensitive and should be protected from light

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Details zu P-Selectin

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Andere Bezeichnung: CD62P / P-Selectin (SELP Produkte)

Synonyme: PSELECT antikoerper, CD62 antikoerper, CD62P antikoerper, GMP140 antikoerper, GRMP antikoerper, LECAM3 antikoerper, PADGEM antikoerper, PSEL antikoerper, GMP-140 antikoerper, Grmp antikoerper, selectin P antikoerper, selectin, platelet antikoerper, Selp antikoerper, SELP antikoerper

Hintergrund: CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond clusterSynonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP

Gen-ID: 6403

NCBI Accession: NP_002996

UniProt: P16109