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DC-SIGN/CD209 Antikörper

CD209 Reaktivität: Human FACS, IF Wirt: Maus Monoclonal MR-1 unconjugated
Produktnummer ABIN181975
  • Target Alle DC-SIGN/CD209 (CD209) Antikörper anzeigen
    DC-SIGN/CD209 (CD209) (CD209)
    Reaktivität
    • 105
    • 27
    • 22
    • 1
    • 1
    Human
    Wirt
    • 71
    • 47
    • 4
    • 1
    Maus
    Klonalität
    • 70
    • 53
    Monoklonal
    Konjugat
    • 60
    • 10
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert
    Applikation
    • 70
    • 52
    • 34
    • 30
    • 26
    • 13
    • 8
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Spezifität
    This antibody recognises DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN, CD209), a 45 kDa C-type lectin that binds ICAM-3.
    Aufreinigung
    Protein G affinity chtromatography
    Immunogen
    Immature myeloid monocyte-derived dendritic cells (MDDCs)
    Klon
    MR-1
    Isotyp
    IgG1
    Top Product
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  • Applikationshinweise
    Immunofluorescence. Flow cytometry: 1/50 - 1/100. Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Clone MR-1 is reported to partially block the functional activity of DC-SIGN (see ref. 2).
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4, containing 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    DC-SIGN/CD209 (CD209) (CD209)
    Andere Bezeichnung
    CD209 / DC-SIGN (CD209 Produkte)
    Hintergrund
    CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1
    Gen-ID
    9606
    UniProt
    Q9NNX6
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