DC-SIGN/CD209 Antikörper

Produktnummer ABIN181974

Der Maus Monoklonal anti-DC-SIGN/CD209 Antikörper (Klon MR-1) (ABIN181974) detektiert spezifisch DC-SIGN/CD209 in FACS, IF und Func. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DC-SIGN/CD209 Antikörper (ABIN181974)

Target: DC-SIGN/CD209 (CD209) (CD209)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Klon: MR-1

Produktdetails anti-DC-SIGN/CD209 Antikörper

Spezifität: This antibodies recognises human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45 kDa C-type lectin that binds ICAM-3 also known as CD209.

Aufreinigung: Protein G affinity chromatography

Endotoxin-Niveau: Low Endotoxin

Immunogen: Immature myeloid monocyte-derived dendritic cells (MDDCs)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Use 10 μL to label 10^6 cells in 100 μL. Immunofluorescence. Functional assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, without preservatives or stbilizers

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.

Haltbarkeit: 6 months

Details zu DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Andere Bezeichnung: CD209 / DC-SIGN

Hintergrund: CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's. Clone MR-1 is reported to partially block the functional activity of DC-SIGN(2).Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

Gen-ID: 9606

UniProt: Q9NNX6