SIGLEC7 Antikörper

Produktnummer ABIN1819168

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SIGLEC7 in WB, ELISA, FACS, IP, Func und DNA Mic. Er zeigt eine Reaktivität gegenüber Human, Rhesusaffen und Affe.

Kurzübersicht für SIGLEC7 Antikörper (ABIN1819168)

Target: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Reaktivität: Human, Rhesusaffen, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SIGLEC7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), DNA Microscopy (DNA Mic)

Klon: S7-7

Produktdetails anti-SIGLEC7 Antikörper

Spezifität: Recognizes human Sialic acid-binding Ig-like lectin 7, otherwise known as CD328, a putative adhesion molecule and member of the Ig superfamily, predominantly expressed by both resting and activated natural killer (NK) cells, and also at lower levels by monocytes, granulocytes, monocyte-derived macrophages and dendritic cells, and a small population of CD8+ memory T cells. Classified as a CD33-related Siglec, Siglec-7 preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid, and acts as a novel inhibitory receptor for NK cells, mediating the inhibition of NK cell cytotoxicity, and implicated in the regulation of NK cell and T cell activation, and hematopoiesis. Clone S7.7 is a blocking antibody see for details, and has been shown to recognize Siglec-7 in Rhesus monkey see for details.

Aufreinigung: Protein G purified

Endotoxin-Niveau: Low Endotoxin

Immunogen: Siglec-7 3T3 transfected cells.

Type of Immunogen: Cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo, Func, IP, WB

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu SIGLEC7

Target: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Andere Bezeichnung: SIGLEC7 / CD328

Hintergrund: Name/Gene ID: SIGLEC7
Family: Immunoglobulin

Synonyms: SIGLEC7, AIRM-1, AIRM1, CD328 antigen, CDw328, CD328, D-siglec, QA79, SIGLEC-7, QA79 membrane protein

Gen-ID: 27036