MBP Antikörper (pThr98)

Produktnummer ABIN181840

Dieses Maus Monoklonal-Antikörper erkennt spezifisch MBP in WB, IHC (fro) und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MBP Antikörper (pThr98) (ABIN181840)

Target: MBP (Myelin Basic Protein (MBP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: 98P-12

Produktdetails anti-MBP Antikörper

Bindungsspezifität: pThr98

Spezifität: This antibody recognises myelin basic protein that is phosphorylated on threonine 98.

Aufreinigung: Purified

Immunogen: Synthetic peptide from human myelin basic protein sequence, phosphorylated on threonine 98.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MBP

Target: MBP (Myelin Basic Protein (MBP))

Andere Bezeichnung: Myelin Basic Protein

Hintergrund: The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.Synonyms: MBP, Myelin membrane encephalitogenic protein

Gen-ID: 4155

NCBI Accession: NP_001020252

UniProt: P02686