CD68 Antikörper (PE)

Produktnummer ABIN181838

Es gibt 1 Publikation für dieses Produkt. Der Ratte Monoklonal anti-CD68 Antikörper wird verwendet zum Nachweis von CD68 in Proben von Maus. Er wurde validiert für FACS.

Kurzübersicht für CD68 Antikörper (PE) (ABIN181838)

Target: CD68 (CD68 Molecule (CD68))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD68 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: FA-11

Produktdetails anti-CD68 Antikörper (PE)

Spezifität: The antibody recognizes CD68. SM1550R does detect surface Macrosialin at low levels in resident Mouse peritoneal macrophages which can be enhanced with thioglycollate stimulation.

Aufreinigung: Affinity Chromatography on Protein G

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow cytometry: use 10 μL of neat antibody to label 10^6 cells in 100 μL. Membrane permeabilisation is required for this application. ABIN181838 does detect surface macrosialin at low levels in resident mouse peritoneal macrophages which can be enhanced with thioglycollate stimulation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1.0 mL distilled water.

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 1 % BSA, 5 % Sucrose

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Referenzen für anti-CD68 Antikörper (PE) (ABIN181838)

Kirby, Beattie, Maroof, van Rooijen, Kaye: "SIGNR1-negative red pulp macrophages protect against acute streptococcal sepsis after Leishmania donovani-induced loss of marginal zone macrophages." in: The American journal of pathology, Vol. 175, Issue 3, pp. 1107-15, (2009) (PubMed).

Details zu CD68

Target: CD68 (CD68 Molecule (CD68))

Andere Bezeichnung: CD68

Hintergrund: Macrosialin is a heavily glycosylated transmembrane protein of 87-115kD, which is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. Macrosialin is the murine homologue of the human macrophage glycoprotein CD68, both are members of the lysosomal-associated membrane protein (lamp) family which are located predominantly within the cells and can be detected by flow cytometry using cell permeablisation.Synonyms: Gp110, Macrophage marker, Macrosialin

Gen-ID: 12514

NCBI Accession: NP_033983

UniProt: P31996