ITGA6 Antikörper (PE)
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- Target Alle ITGA6 Antikörper anzeigen
- ITGA6 (Integrin, alpha 6 (ITGA6))
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Reaktivität
- Human, Maus, Hund, Schwein, Affe
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser ITGA6 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- This antibody recognises CD49F (VLA-6 alpha chain). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts.VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. We recommend the use of SM038Afor this purpose.
- Aufreinigung
- Affinity chromatography on Protein G
- Immunogen
- BALB/c mouse mammary tumour cells. Spleen cells from immunised Sprague-Dawley rats were fused with cells of the SP2/0 mouse myeloma cell line.
- Klon
- NKI-GoH3
- Isotyp
- IgG2a
- Top Product
- Discover our top product ITGA6 Primärantikörper
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- Applikationshinweise
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Flow Cytometry: Neat - 1/5, Use 10 μL of the suggested working dilution to label 10^6 platelets in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Restore with 1.0 mL distilled water.
- Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- ITGA6 (Integrin, alpha 6 (ITGA6))
- Andere Bezeichnung
- CD49f / ITGA6 (ITGA6 Produkte)
- Synonyme
- CD49f antikoerper, ITGA6B antikoerper, VLA-6 antikoerper, 5033401O05Rik antikoerper, AI115430 antikoerper, Cd49f antikoerper, ITGA6 antikoerper, inta6 antikoerper, im:6897425 antikoerper, itga6 antikoerper, si:dkey-32o22.1 antikoerper, wu:fb80g02 antikoerper, LOC100221694 antikoerper, si:dkey-18j14.1 antikoerper, wu:fl20e08 antikoerper, zgc:113088 antikoerper, integrin subunit alpha 6 antikoerper, integrin alpha 6 antikoerper, integrin subunit alpha 6 L homeolog antikoerper, integrin, alpha 6a antikoerper, integrin, alpha 6b antikoerper, ITGA6 antikoerper, Itga6 antikoerper, itga6.L antikoerper, itga6a antikoerper, itga6b antikoerper
- Hintergrund
- CD49F (VLA-6 alpha chain)is a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone NKI-GoH3 reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1).Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6
- Gen-ID
- 3655
- NCBI Accession
- NP_000201
- UniProt
- P23229
- Pathways
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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