IL-19 Antikörper

Produktnummer ABIN181616

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IL-19 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IL-19 Antikörper (ABIN181616)

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-IL-19 Antikörper

Spezifität: This antibody detects Interleukin-19.

Aufreinigung: Affinity Chromatography employing immobilized Human IL19 matrix.

Immunogen: Highly pure (>98%) E.coli derived recombinant Human IL-19

Anwendungsinformationen

Applikationshinweise: ELISA: Indirect: To detect hIL-19 by indirect ELISA (using 100 μL/well antibody solution) aconcentration of 0.5 - 2.0 μg/mL of this antibody is required. In conjunction withcompatible secondary reagents, it allows the detection of at least 0.2 - 0.4 ng/well ofrecombinant hIL-19. Sandwich: To detect hIL-19 by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.5 - 2.0 μg/mL is required. In conjunction with Biotinylated Anti-HumanIL-19 as a detection antibody, it allows the detection of at least 0.2 - 0.4 ng/well ofrecombinant hIL-19. Western Blot: To detect hIL-19 by Western Blot analysis this antibody can be used at aconcentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hIL-19 is 1.5 - 3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile water to a concentration of 0.1 - 1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the lyophilized antibody at -20 °C. Following reconstitution, the product ist stable at 2-8 °C for up one week or (in aliquots) at -20 °C for up to six months.

Details zu IL-19

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Andere Bezeichnung: Interleukin-19 / IL19

Hintergrund: IL19 is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Little is known about the biologic function and gene regulation of IL19. Alternatively spliced transcript variants encoding distinct isoforms have been described.Synonyms: IL-19, Melanoma differentiation-associated protein-like protein, NG.1, ZMDA

Gen-ID: 29949

NCBI Accession: NP_037503

UniProt: Q9UHD0