BMP4 Antikörper

Produktnummer ABIN181146

Produktdetails anti-BMP4 Antikörper

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BMP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Functional Studies (Func)

Spezifität: This antibody detects BMP4.

Produktmerkmale: Synonyms: BMP2B, BMP-2B, BMP-4, DVR4, Bone morphogenetic protein 4

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Highly pure (>98%) recombinant Human BMP-4

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: In a sandwich ELISA (assuming 100μL/well), a concentration of 4.0-8.0 μg/mL of thisantibody will detect at least 2000 pg/mL of recombinant Human BMP-4 when used inconjunction with compatible secondary reagents. Western Blot: To detect Human BMP-4 by Western Blot analysis this antibody can be usedat a concentration of 0.25-0.50 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant Human BMP-4 is 2.0-4.0 ng/lane, undernon-reducing conditions. Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhBMP-4 (5.0 ng/mL), a concentration of 0.4-0.6 μg/mL of this antibody is required.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile water to a concentration of 1.0 mg/mL.

Buffer: PBS without preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: The lyophilized antibody is stable at room temperature for one month or at -20 °C forlonger. Following reconstitution it is stable at 2-8 °C for six weeks. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu BMP4

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Andere Bezeichnung: BMP4 (BMP4 Produkte)

Synonyme: BMP2B antikoerper, BMP2B1 antikoerper, MCOPS6 antikoerper, OFC11 antikoerper, ZYME antikoerper, Bmp-4 antikoerper, Bmp2b antikoerper, Bmp2b-1 antikoerper, Bmp2b1 antikoerper, BOMPR4A antikoerper, bmp-4 antikoerper, zbmp-4 antikoerper, zgc:100779 antikoerper, BMP-4 antikoerper, XBMP-4 antikoerper, bmp2b antikoerper, bmp2b1 antikoerper, bmp4 antikoerper, ofc11 antikoerper, xbmp4 antikoerper, zyme antikoerper, BMP4 antikoerper, bone morphogenetic protein 4 antikoerper, bone morphogenetic protein 4 L homeolog antikoerper, bone morphogenetic protein 4 S homeolog antikoerper, BMP4 antikoerper, Bmp4 antikoerper, bmp4 antikoerper, bmp4.L antikoerper, bmp4.S antikoerper

Hintergrund: BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.Synonyms: BMP-2B, BMP-4, BMP2B, Bone morphogenetic protein 4, DVR4

Gen-ID: 652

UniProt: P12644

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development