IDO1 Antikörper (AA 78-184)

Produktnummer ABIN180889

Dieser Maus Monoklonal Antikörper detektiert spezifisch IDO1 in WB und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für IDO1 Antikörper (AA 78-184) (ABIN180889)

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IDO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 10-01-14

Produktdetails anti-IDO1 Antikörper

Bindungsspezifität: AA 78-184

Spezifität: This Monoclonal antibody 10.1 recognizes Indoleamine-pyrrole 2,3-dioxygenase (IDO), an enzyme responsible for the catabolism of Tryptophan to N-Formlkynurenine and Kynurenine. In Western Blotting, it recognizes a 45 kDa band in IFN-gamma treated Human cell lines. This antibody recognizes a slightly lower Molecular Weight band in Mouse IDO compared to its Human counterpart.

Produktmerkmale: Synonyms: IDO1, IDO, INDO, Indoleamine 2, 3-dioxygenase 1, EC=1.13.11.52, 3-dioxygenase,Indoleamine-pyrrole 2

Aufreinigung: Purified

Immunogen: Peptide corresponding to amino acids 78-184 of human IDO fused to GST

Isotyp: IgG3

Anwendungsinformationen

Applikationshinweise: Western Blot. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu IDO1

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Andere Bezeichnung: IDO1 / INDO

Hintergrund: With the exception of tryptophan oxidase in hepatocytes, IDO is the only enzyme that degrades the amino acid tryptophan to kynurenine. Chlamydial pathogens require tryptophan for growth. IDO can lower available tryptophan in target cells leading to conversion of the pathogen to persistant forms, with significance in the progression to chronic infection with its associated pathological effects.Synonyms: 3-dioxygenase, 3-dioxygenase 1, EC=1.13.11.52, IDO, IDO1, INDO, Indoleamine 2, Indoleamine-pyrrole 2

Gen-ID: 3620

UniProt: P14902

Pathways: Activated T Cell Proliferation