FOLR1 Antikörper

Produktnummer ABIN180849

Dieses Anti-FOLR1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von FOLR1 in EIA. Geeignet für Human und Rind (Kuh).

Kurzübersicht für FOLR1 Antikörper (ABIN180849)

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Reaktivität: Human, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FOLR1 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Klon: SF55 (BGN-1210-55)

Produktdetails anti-FOLR1 Antikörper

Spezifität: This antibody reacts with Folate Binding Protein (FBP) a 30 kDa protein with a high affinity for folate and several reduced folic acid derivatives, that mediates the intracelullar delivery of 5-Methyl-Tetrahydrofolate. Membrane bound and soluble forms of a high affinity FBP have been found in kidney, placenta, serum, milk, and several cell lines.

Produktmerkmale: Synonyms: FR-alpha, Folate receptor 1, MOv18, KB cells FBP, FOLR1, FOLR, Adult folate-binding protein,Ovarian tumor-associated antigen MOv18

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Folate binding protein from bovine milk.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu FOLR1

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Andere Bezeichnung: Folate Receptor alpha

Hintergrund: Folate Binding Protein, has a high affinity for folic acid and for several reduced folic acid derivatives and mediates delivery of 5 methyltetrahydrofolate to the interior of cells. Membrane bound and soluble forms of a high affinity folate binding protein have been found in kidney, placenta, serum, milk, and in several cell lines. The 2 forms have similar binding characteristics for folates, are immunologically crossreactive, and, based upon limited amino acid sequence data, are nearly identical. There may be a precursor product relationship between the membrane and soluble forms, the membrane form having additional amino acid residues and greater molecular weight. The membrane form has been shown to mediate the transport of folate in cells grown in physiologic concentrations of folate. A function for the soluble form, which is found in serum, milk, and urine, has not been identified.Synonyms: Adult folate-binding protein, FOLR, FOLR1, FR-alpha, Folate receptor 1, KB cells FBP, MOv18, Ovarian tumor-associated antigen MOv18

Gen-ID: 2348

UniProt: P15328

Pathways: Dicarboxylic Acid Transport