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Human Adenovirus type 1 (HAdV-1) Antikörper

Dieses Anti--Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von in EIA, ID und FACS. Geeignet für Adenovirus.
Produktnummer ABIN180711

Kurzübersicht für Human Adenovirus type 1 (HAdV-1) Antikörper (ABIN180711)

Target

Human Adenovirus type 1 (HAdV-1)

Reaktivität

Adenovirus

Wirt

  • 2
  • 1
Maus

Klonalität

  • 2
  • 1
Monoklonal

Konjugat

  • 3
Unkonjugiert

Applikation

  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Enzyme Immunoassay (EIA), Immunodiffusion (ID), Flow Cytometry (FACS)

Klon

8C4
  • Produktmerkmale

    Synonyms: Adenovirus antibody

    Aufreinigung

    Affinity chromatography on Protein A

    Immunogen

    Hexon antigen of human and canine adenoviruses (Type 1).

    Isotyp

    IgG2a
  • Applikationshinweise

    ELISA. Immunodiffusion. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    PBS containing 0.09 % Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at +4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
    Shelf life: one year from despatch.

    Haltbarkeit

    12 months
  • Target

    Human Adenovirus type 1 (HAdV-1)

    Andere Bezeichnung

    Adenovirus Type 1

    Substanzklasse

    Virus

    Hintergrund

    Adenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e. common colds). Forty-seven known serotypes have been isolated since they were first discovered in 1953 with 3 types known to cause gastroenteritis. Several types have oncogenic potential though most cause self-limiting febrile illnesses characterised by inflammation of conjunctivae and the respiratory tract. The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections. It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods. In patients experiencing immunosuppression (e.g. AIDS) it can be reactivated causing disease. Hexon protein is a major coat protein of adenoviruses. Adenoviruses capsids have three principal protein components: the hexon, the penton, and the fiber. Hexon consists of three subunits together forming two major components of different morphological symmetry. A triangular top with three towers of density is superimposed on a more bulky pseudo hexagonal base. The symmetry of the top is in accord with the trimeric nature of hexon, but that of the base derives from the molecular function, which is to provide a densely packed impenetrable protective outer layer for the virion.
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