Complement C4c Antikörper
Kurzübersicht für Complement C4c Antikörper (ABIN1804101)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Marke
- IHC-plus™
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Spezifität
- Recognizes complement component 4c (C4c). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b's alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonization and activation of the classical pathway. iC4b is further degraded into the inactive fragments C4d and C4c. C4c consists of two a-chain fragments, alpha 4 (13 kD) and alpha 3 (25 kD) linked to a beta chain through disulphide bridges and a gamma chain. It is expressed in the blood plasma. Binds both C4c and C4 and so is not suitable for all ELISA applications.
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Aufreinigung
- Protein A purified from ascites
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Immunogen
- Purified human C4c.
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Isotyp
- IgG1
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Applikationshinweise
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Approved: ELISA, Flo, IHC, IHC-Fr, IHC-P (10 μg/mL), WB
Usage: ELISA: Binds both C4c and C4 and so is not suitable for all ELISA applications. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Borate buffered saline, 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Aliquot to avoid repeated freezing and thawing. Store undiluted.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
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- Complement C4c (C4c) (Complement Component C4c (C4c))
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Andere Bezeichnung
- Complement C4c
Target
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