Profilin Antikörper (AA 1-140)

Produktnummer ABIN1742559

Dieser Anti-Profilin Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von Profilin in WB, IHC und IHC (p). Geeignet für Human, Rind (Kuh), Meerschweinchen, Opossum und Kaninchen. Dieses Primary Antibody wurde in 6+ Publikationen zitiert.

Kurzübersicht für Profilin Antikörper (AA 1-140) (ABIN1742559)

Target: Profilin (PFN)

Reaktivität: Human, Rind (Kuh), Meerschweinchen, Opossum, Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Profilin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 2H11

Produktdetails anti-Profilin Antikörper

Bindungsspezifität: AA 1-140

Verwendungszweck: Mouse anti-Bovine Profilin IgG

Spezifität: Specific for profilin 1.

Kreuzreaktivität (Details): Reacts with: human (P07737), cow, rabbit, Guinea pig, opossum. No signal: mouse (P62962). Other species not tested yet.

Aufreinigung: purified IgG

Immunogen: Recombinant protein corresponding to AA 1 to 140 from bovine Profilin1 (UniProt Id: P02584)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB:1 : 500 up to 1 : 5000 IHC:yes IHC-P:1 : 1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS.

Handhabung: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Lagerung: -20 °C,-80 °C,4 °C

Informationen zur Lagerung: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!

Referenzen für anti-Profilin Antikörper (ABIN1742559)

Lorente, Syriani, Morales: "Actin filaments at the leading edge of cancer cells are characterized by a high mobile fraction and turnover regulation by profilin I." in: PLoS ONE, Vol. 9, Issue 1, pp. e85817, (2014) (PubMed).

Giesemann, Schwarz, Nawrotzki, Berhörster, Rothkegel, Schlüter, Schrader, Schindelin, Mendel, Kirsch, Jockusch: "Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 23, Issue 23, pp. 8330-9, (2003) (PubMed).

Giesemann, Rathke-Hartlieb, Rothkegel, Bartsch, Buchmeier, Jockusch, Jockusch: "A role for polyproline motifs in the spinal muscular atrophy protein SMN. Profilins bind to and colocalize with smn in nuclear gems." in: The Journal of biological chemistry, Vol. 274, Issue 53, pp. 37908-14, (2000) (PubMed).

Janke, Schlüter, Jandrig, Theile, Kölble, Arnold, Grinstein, Schwartz, Estevéz-Schwarz, Schlag, Jockusch, Scherneck: "Suppression of tumorigenicity in breast cancer cells by the microfilament protein profilin 1." in: The Journal of experimental medicine, Vol. 191, Issue 10, pp. 1675-86, (2000) (PubMed).

Schlüter, Schleicher, Jockusch: "Effects of single amino acid substitutions in the actin-binding site on the biological activity of bovine profilin I." in: Journal of cell science, Vol. 111 ( Pt 22), pp. 3261-73, (1999) (PubMed).

Wiedemann, Giehl, Almo, Fedorov, Girvin, Steinberger, Rüdiger, Ortner, Sippl, Dolecek, Kraft, Jockusch, Valenta: "Molecular and structural analysis of a continuous birch profilin epitope defined by a monoclonal antibody." in: The Journal of biological chemistry, Vol. 271, Issue 47, pp. 29915-21, (1997) (PubMed).

Details zu Profilin

Target: Profilin (PFN)

Andere Bezeichnung: Profilin

Hintergrund:

Synonyms: profilin

Antigen Information: Profilins are regulators of the microfilament network

UniProt: P02584