GluN 2B (AA 42-60) Antikörper

Produktnummer ABIN1742497

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GluN 2B in WB und IP. Es zeigt Reaktivität gegenüber Proben von Ratte und Maus. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für GluN 2B (AA 42-60) Antikörper (ABIN1742497)

Target: GluN 2B

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails

Bindungsspezifität: AA 42-60

Verwendungszweck: Rabbit anti-GluN2B antibody

Spezifität: Specific for GluN 2B

Kreuzreaktivität (Details): Reacts with: rat (Q00960), mouse (Q01097). Other species not tested yet.

Aufreinigung: affinity purified

Immunogen: Synthetic peptide corresponding to AA 42 to 60 from rat GluN2B (UniProt Id: Q00960)

Anwendungsinformationen

Applikationshinweise: WB:1 : 1000 ICC:not tested yet IHC:not tested yet IHC-P:not tested yet

Kommentare:

IP: For most effective IP use the solubilization protocol described in the ELISA protocol. Consider that protein-protein interaction may be affected.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Lagerung: -20 °C,-80 °C,4 °C

Informationen zur Lagerung: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

Referenzen

Szutorisz, DiNieri, Sweet, Egervari, Michaelides, Carter, Ren, Miller, Blitzer, Hurd: "Parental THC exposure leads to compulsive heroin-seeking and altered striatal synaptic plasticity in the subsequent generation." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 39, Issue 6, pp. 1315-23, (2014) (PubMed).

Gut, Beske, Hubbard, Lyman, Hamilton, McNutt: "Novel application of stem cell-derived neurons to evaluate the time- and dose-dependent progression of excitotoxic injury." in: PLoS ONE, Vol. 8, Issue 5, pp. e64423, (2013) (PubMed).

Antigendetails

Target: GluN 2B

Andere Bezeichnung: GluN2B

Hintergrund:

Synonyms: NMDA-receptor 2 B, GluN2B, GluN 2B, glutamate receptor, NR2B, GRIN2B

Antigen Information: GluN2A and B are subunits of ionotropic NMDA type glutamate receptors

UniProt: Q00960