SHANK3 Antikörper (AA 1055-1616)
Kurzübersicht für SHANK3 Antikörper (AA 1055-1616) (ABIN1742347)
Target
Alle SHANK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1055-1616
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Spezifität
- Specific for shank 3.
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Immunogen
- Recombinant protein (aa 1055-1616 of rat shank 3).
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Applikationshinweise
- WB: 1:1000, ICC: 1:500,
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Kommentare
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IHC: For best results the antibody requires a mild fixation protocol (2 % PFA in sodium acetate buffer, pH 6).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- For reconstitution add 200µl H2O.
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Konservierungsmittel
- Azide and BSA free
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Handhabung
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Reconstitute and aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized.
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: "Zinc Stabilizes Shank3 at the Postsynaptic Density of Hippocampal Synapses." in: PLoS ONE, Vol. 11, Issue 5, pp. e0153979, (2016) (PubMed).
: "Reduced Glutamate Release in Adult BTBR Mouse Model of Autism Spectrum Disorder." in: Neurochemical research, Vol. 41, Issue 11, pp. 3129-3137, (2016) (PubMed).
: "Inhibition of IL-6 trans-signaling in the brain increases sociability in the BTBR mouse model of autism." in: Biochimica et biophysica acta, Vol. 1862, Issue 10, pp. 1918-25, (2016) (PubMed).
: "Effects of trace metal profiles characteristic for autism on synapses in cultured neurons." in: Neural plasticity, Vol. 2015, pp. 985083, (2015) (PubMed).
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: "Zinc Stabilizes Shank3 at the Postsynaptic Density of Hippocampal Synapses." in: PLoS ONE, Vol. 11, Issue 5, pp. e0153979, (2016) (PubMed).
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- SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))
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Andere Bezeichnung
- Shank 3
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Hintergrund
- Synonyms: ProSAP2, SPANK2
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Pathways
- Synaptic Membrane, Tube Formation, Regulation of long-term Neuronal Synaptic Plasticity
Target
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