Homer 1b/c (C-Term) Antikörper

Produktnummer ABIN1742339

Der Kaninchen Polyklonal Anti- Antikörper wurde für WB, ICC, IHC und IP validiert. Er ist geeignet, in Proben von Human, Maus und Ratte zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für Homer 1b/c (C-Term) Antikörper (ABIN1742339)

Target: Homer 1b/c

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-Homer1b/c antibody

Spezifität: Specific for homer 1b and 1c

Kreuzreaktivität (Details): Reacts with: human (Q86YM7-1), rat (Q9Z214-2, Q9Z214-1), mouse. Other species not tested yet.

Aufreinigung: affinity purified

Immunogen: Recombinant protein corresponding to the c-terminal half of human Homer 1b (UniProt Id: Q86YM7-1)

Anwendungsinformationen

Applikationshinweise: WB:1 : 1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Lagerung: -20 °C,-80 °C,4 °C

Informationen zur Lagerung: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

Referenzen

Yoon, Piguel, Khalatyan, Dionisio, Savas, Penzes: "Homer1 promotes dendritic spine growth through ankyrin-G and its loss reshapes the synaptic proteome." in: Molecular psychiatry, (2021) (PubMed).

Kim, Kong, Yamamoto, Kuramoto, Huang, Wang, Hong, Xiao, Levine, Qiu, Zhao, Miller, Dong, Meltzer, Xu, He: "An autophagy-related protein Becn2 regulates cocaine reward behaviors in the dopaminergic system." in: Science advances, Vol. 7, Issue 8, (2021) (PubMed).

Tao-Cheng, Thein, Yang, Reese, Gallant: "Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation." in: Neuroscience, Vol. 266, pp. 80-90, (2014) (PubMed).

Antigendetails

Target: Homer 1b/c

Andere Bezeichnung: Homer1b/c

Hintergrund:

Synonyms: VesL 1, Syn47, Homer1 b, Homer1 c, Homer1 bc

Antigen Information: Homer1 , 2 and 3 are post synaptic density (PSD) proteins involved in the targeting of glutamate receptors

UniProt: Q86YM7