SNAPIN Antikörper (C-Term)

Produktnummer ABIN1742322

Dieses Anti-SNAPIN-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SNAPIN in WB. Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für SNAPIN Antikörper (C-Term) (ABIN1742322)

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAPIN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SNAPIN Antikörper

Bindungsspezifität: AA 117-136, C-Term

Spezifität: Specific for snapin.

Aufreinigung: antiserum

Immunogen: Synthetic peptide TARRRAMLDSGVYPPGSPSK (aa 117-136 in rat) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.

Anwendungsinformationen

Applikationshinweise: WB: 1 : 100 - 1 : 5000 (AP staining)
IP: not recommended
ICC: not tested yet
IHC: not recommended

Kommentare:

Since snapin is present in very low concentrations long exposure time is recommended.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS

Handhabung: Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

Referenzen für anti-SNAPIN Antikörper (ABIN1742322)

Zhou, Cai, Xie, Sheng: "Snapin recruits dynein to BDNF-TrkB signaling endosomes for retrograde axonal transport and is essential for dendrite growth of cortical neurons." in: Cell reports, Vol. 2, Issue 1, pp. 42-51, (2012) (PubMed).

Zhang, Wada, Yasuhara, Iseda, Eguchi, Fukui, Yang, Yamagata, Hiesberger, Igarashi, Zhang, Wang, Akagi, Kanwar, Makino: "The role for HNF-1beta-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells." in: PLoS ONE, Vol. 2, Issue 5, pp. e414, (2007) (PubMed).

Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

Vites, Rhee, Schwarz, Rosenmund, Jahn: "Reinvestigation of the role of snapin in neurotransmitter release." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26251-6, (2004) (PubMed).

Details zu SNAPIN

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Andere Bezeichnung: Snapin

Hintergrund: Synonyms: Snapap

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis