APP Antikörper (C-Term)

Produktnummer ABIN1742281

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch APP in WB, IHC und ICC. Er zeigt eine Reaktivität gegenüber Maus, Ratte, Huhn und Frosch und wurde in 1 Publikation erwähnt.

Kurzübersicht für APP Antikörper (C-Term) (ABIN1742281)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reaktivität: Maus, Ratte, Huhn, Frosch

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Produktdetails anti-APP Antikörper

Bindungsspezifität: C-Term

Spezifität: Specific for APP.

Aufreinigung: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Synthetic peptide GYENPTYKFFEQMQN corresponding to the C-terminus of APP coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.

Anwendungsinformationen

Applikationshinweise: WB: 1 : 500 up to 1 : 1000 (AP staining)
IP: not tested yet
ICC: 1 : 500
IHC-P: 1 : 2000

Kommentare:

IHC/IHC-P: The affinity purified antibody is highly recommended.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handhabung: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Lagerung: -20 °C

Informationen zur Lagerung: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

Referenzen für anti-APP Antikörper (ABIN1742281)

Groemer, Thiel, Holt, Riedel, Hua, Hüve, Wilhelm, Klingauf: "Amyloid precursor protein is trafficked and secreted via synaptic vesicles." in: PLoS ONE, Vol. 6, Issue 4, pp. e18754, (2011) (PubMed).

Details zu APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Andere Bezeichnung: APP

Pathways: Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour