DLG4 Antikörper (AA 18-32)

Produktnummer ABIN1742271

Dieses Anti-DLG4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DLG4 in WB und IP. Geeignet für Ratte, Human, Maus und Hamster. Dieses Primary Antibody wurde in 10+ Publikationen zitiert.

Kurzübersicht für DLG4 Antikörper (AA 18-32) (ABIN1742271)

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Reaktivität: Ratte, Human, Maus, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLG4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-DLG4 Antikörper

Bindungsspezifität: AA 18-32

Spezifität: Specific for PSD 95.

Aufreinigung: antiserum

Immunogen: Synthetic peptide DTPPLEHSPAHLPNQ (aa 18-32 in rat) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.

Anwendungsinformationen

Applikationshinweise: WB: 1 : 1000 (AP staining)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS

Handhabung: Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

Referenzen für anti-DLG4 Antikörper (ABIN1742271)

Casciati, Dobos, Antonelli, Benedek, Kempf, Bellés, Balogh, Tanori, Heredia, Atkinson, von Toerne, Azimzadeh, Saran, Sáfrány, Benotmane, Linares-Vidal, Tapio, Lumniczky, Pazzaglia: "Age-related effects of X-ray irradiation on mouse hippocampus." in: Oncotarget, Vol. 7, Issue 19, pp. 28040-58, (2018) (PubMed).

Bitencourt, Alpár, Cinquina, Ferreira, Pinheiro, Lemos, Ledent, Takahashi, Sialana, Lubec, Cunha, Harkany, Köfalvi: "Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents." in: Neurochemistry international, Vol. 90, pp. 72-84, (2015) (PubMed).

Dervola, Johansen, Walaas, Fonnum: "Gender-dependent and genotype-sensitive monoaminergic changes induced by polychlorinated biphenyl 153 in the rat brain." in: Neurotoxicology, Vol. 50, pp. 38-45, (2015) (PubMed).

Li, Hu, Höfer, Wong, Cooper, Birnbaum, Hammer, Hofmann: "DHHC5 interacts with PDZ domain 3 of post-synaptic density-95 (PSD-95) protein and plays a role in learning and memory." in: The Journal of biological chemistry, Vol. 285, Issue 17, pp. 13022-31, (2010) (PubMed).

Smalla, Sahin, Putzke, Tischmeyer, Gundelfinger, Kreutz: "Altered postsynaptic-density-levels of caldendrin in the para-chloroamphetamine-induced serotonin syndrome but not in the rat ketamine model of psychosis." in: Neurochemical research, Vol. 34, Issue 8, pp. 1405-9, (2009) (PubMed).

Norris, Strickland: "Modulation of NR2B-regulated contextual fear in the hippocampus by the tissue plasminogen activator system." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 33, pp. 13473-8, (2007) (PubMed).

Van Damme, Bogaert, Dewil, Hersmus, Kiraly, Scheveneels, Bockx, Braeken, Verpoorten, Verhoeven, Timmerman, Herijgers, Callewaert, Carmeliet, Van Den Bosch, Robberecht: "Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 37, pp. 14825-30, (2007) (PubMed).

Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

Wong, Schlichter: "Differential recruitment of Kv1.4 and Kv4.2 to lipid rafts by PSD-95." in: The Journal of biological chemistry, Vol. 279, Issue 1, pp. 444-52, (2003) (PubMed).

Von Kriegstein, Schmitz, Link, Südhof: "Distribution of synaptic vesicle proteins in the mammalian retina identifies obligatory and facultative components of ribbon synapses." in: The European journal of neuroscience, Vol. 11, Issue 4, pp. 1335-48, (1999) (PubMed).

Details zu DLG4

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Andere Bezeichnung: PSD 95

Hintergrund: Synonyms: SAP 90, DLG 4

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity