DLG4 Antikörper (AA 18-32)

Produktnummer ABIN1742271

Dieser Anti-DLG4 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von DLG4 in WB und IP. Geeignet für Ratte, Human, Maus und Hamster. Dieses Primary Antibody wurde in 10+ Publikationen zitiert.

Kurzübersicht für DLG4 Antikörper (AA 18-32) (ABIN1742271)

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Reaktivität: Ratte, Human, Maus, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLG4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-DLG4 Antikörper

Bindungsspezifität: AA 18-32

Verwendungszweck: Rabbit anti-PSD95 antiserum

Spezifität: Specific for PSD 95.

Kreuzreaktivität (Details): Reacts with: human (P78352), rat (P31016), mouse (Q62108), hamster. Other species not tested yet.

Aufreinigung: antiserum

Immunogen: Synthetic peptide corresponding to AA 18 to 32 from rat PSD95 (UniProt Id: P31016)

Anwendungsinformationen

Applikationshinweise: WB:1 : 1000 , IP:yes ICC:not recommended IHC:not recommended IHC-P:not tested yet

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

Handhabung: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

Referenzen für anti-DLG4 Antikörper (ABIN1742271)

Casciati, Dobos, Antonelli, Benedek, Kempf, Bellés, Balogh, Tanori, Heredia, Atkinson, von Toerne, Azimzadeh, Saran, Sáfrány, Benotmane, Linares-Vidal, Tapio, Lumniczky, Pazzaglia: "Age-related effects of X-ray irradiation on mouse hippocampus." in: Oncotarget, Vol. 7, Issue 19, pp. 28040-58, (2018) (PubMed).

Bitencourt, Alpár, Cinquina, Ferreira, Pinheiro, Lemos, Ledent, Takahashi, Sialana, Lubec, Cunha, Harkany, Köfalvi: "Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents." in: Neurochemistry international, Vol. 90, pp. 72-84, (2015) (PubMed).

Dervola, Johansen, Walaas, Fonnum: "Gender-dependent and genotype-sensitive monoaminergic changes induced by polychlorinated biphenyl 153 in the rat brain." in: Neurotoxicology, Vol. 50, pp. 38-45, (2015) (PubMed).

Li, Hu, Höfer, Wong, Cooper, Birnbaum, Hammer, Hofmann: "DHHC5 interacts with PDZ domain 3 of post-synaptic density-95 (PSD-95) protein and plays a role in learning and memory." in: The Journal of biological chemistry, Vol. 285, Issue 17, pp. 13022-31, (2010) (PubMed).

Smalla, Sahin, Putzke, Tischmeyer, Gundelfinger, Kreutz: "Altered postsynaptic-density-levels of caldendrin in the para-chloroamphetamine-induced serotonin syndrome but not in the rat ketamine model of psychosis." in: Neurochemical research, Vol. 34, Issue 8, pp. 1405-9, (2009) (PubMed).

Norris, Strickland: "Modulation of NR2B-regulated contextual fear in the hippocampus by the tissue plasminogen activator system." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 33, pp. 13473-8, (2007) (PubMed).

Van Damme, Bogaert, Dewil, Hersmus, Kiraly, Scheveneels, Bockx, Braeken, Verpoorten, Verhoeven, Timmerman, Herijgers, Callewaert, Carmeliet, Van Den Bosch, Robberecht: "Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 37, pp. 14825-30, (2007) (PubMed).

Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

Wong, Schlichter: "Differential recruitment of Kv1.4 and Kv4.2 to lipid rafts by PSD-95." in: The Journal of biological chemistry, Vol. 279, Issue 1, pp. 444-52, (2003) (PubMed).

Von Kriegstein, Schmitz, Link, Südhof: "Distribution of synaptic vesicle proteins in the mammalian retina identifies obligatory and facultative components of ribbon synapses." in: The European journal of neuroscience, Vol. 11, Issue 4, pp. 1335-48, (1999) (PubMed).

Details zu DLG4

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Andere Bezeichnung: PSD95

Hintergrund:

Synonyms: SAP 90, DLG 4, Disks large homolog 4, DLGH 4, SAP90, PSD-95, PSD 95, SAP 90

Antigen Information: PSD 95 is a component of postsynaptic densities in central synapses

UniProt: P31016

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity