Complexin 1, 2 (AA 45-81) Antikörper

Produktnummer ABIN1742265

Zitiert in 5+ Publikationen. Der Kaninchen Polyklonal anti-Complexin 1, 2 Antikörper (ABIN1742265) detektiert spezifisch Complexin 1, 2 in ICC, IHC, IHC (p), IP und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Maus, Ratte, Human, Rind (Kuh), Meerschweinchen, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für Complexin 1, 2 (AA 45-81) Antikörper (ABIN1742265)

Target: Complexin 1, 2

Reaktivität: Maus, Ratte, Human, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)

Güteklasse: KO Validated

Produktdetails

Bindungsspezifität: AA 45-81

Verwendungszweck: anti-Complexin1/2

Spezifität: Recognizes complexin 1 and 2.

Kreuzreaktivität (Details): Reacts with: human (O14810, Q6PUV4), rat (P63041, P84087), mouse (P63040, P84086), Guinea pig, cow, zebrafish, rabbit. Other species not tested yet.

Aufreinigung: antiserum

Immunogen: Synthetic peptide corresponding to AA 45 to 81 from mouse Complexin2 (UniProt Id: P84086)

Anwendungsinformationen

Applikationshinweise: WB:1 : 1000 up to 1 : 20000 ICC:1 : 200 up to 1 : 500, IHC:1 : 500, IHC-P:1 : 200,

Kommentare:

IP: Co-immunoprecipitates the SNARE complex.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

Handhabung: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

Referenzen

Getz, Visser, Bell, Xu, Flynn, Zaidi, Syed: "Two proteolytic fragments of menin coordinate the nuclear transcription and postsynaptic clustering of neurotransmitter receptors during synaptogenesis between Lymnaea neurons." in: Scientific reports, Vol. 6, pp. 31779, (2016) (PubMed).

Wilhelm, Mandad, Truckenbrodt, Kröhnert, Schäfer, Rammner, Koo, Claßen, Krauss, Haucke, Urlaub, Rizzoli: "Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins." in: Science (New York, N.Y.), Vol. 344, Issue 6187, pp. 1023-8, (2014) (PubMed).

Tsai, Brewis, van Maaren, Gadella: "Involvement of complexin 2 in docking, locking and unlocking of different SNARE complexes during sperm capacitation and induced acrosomal exocytosis." in: PLoS ONE, Vol. 7, Issue 3, pp. e32603, (2012) (PubMed).

Lee, Brecha: "Immunocytochemical evidence for SNARE protein-dependent transmitter release from guinea pig horizontal cells." in: The European journal of neuroscience, Vol. 31, Issue 8, pp. 1388-401, (2010) (PubMed).

Falkowski, Thomas, Groblewski: "Complexin 2 modulates vesicle-associated membrane protein (VAMP) 2-regulated zymogen granule exocytosis in pancreatic acini." in: The Journal of biological chemistry, Vol. 285, Issue 46, pp. 35558-66, (2010) (PubMed).

Antigendetails

Target: Complexin 1, 2

Andere Bezeichnung: Complexin 1/2

Hintergrund: CPX 1, CPX1, CPX 2, CPX2, Synaphin-1, complexin 1, complexin 2, SNARE associated, eye-retina, 2

UniProt: P84086