Rab3c Antikörper
Kurzübersicht für Rab3c Antikörper (ABIN1742212)
Target
Alle Rab3c Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Rabbit anti-Rab3c antibody
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Spezifität
- Specific for Rab 3c.
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Kreuzreaktivität (Details)
- Reacts with: human (Q96E17), rat (P62824), mouse (P62823), monkey, cow. No signal: zebrafish. Other species not tested yet.
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Aufreinigung
- affinity purified
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Applikationshinweise
- WB:1 : 1000 , IP:yes ICC:1 : 500, IHC:not tested yet IHC-P:not tested yet
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Kommentare
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This antibody has been affinity purified with a peptide consisting only of the Rab 3c specific epitope NTRLKETPPPPQPN (aa 211 - 224) of the human protein.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.
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Buffer
- PBS. Albumin and azide were added for stabilization.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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Lagerung
- -20 °C,-80 °C,4 °C
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Informationen zur Lagerung
- Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!
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: "BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer's disease models." in: Scientific reports, Vol. 6, pp. 33427, (2016) (PubMed).
: "Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 40, pp. 13441-53, (2010) (PubMed).
: "Complexin II plays a positive role in Ca2+-triggered exocytosis by facilitating vesicle priming." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 49, pp. 19538-43, (2008) (PubMed).
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: "BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer's disease models." in: Scientific reports, Vol. 6, pp. 33427, (2016) (PubMed).
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- Rab3c (RAB3C, Member RAS Oncogene Family (Rab3c))
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Andere Bezeichnung
- Rab3c
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Hintergrund
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Synonyms: Ras-related protein 3C
Antigen Information: Rab3 proteins are the major Rab isoforms in brain and are highly enriched on synaptic vesicles
Target
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