Rab3c Antikörper (AA 154-227)

Produktnummer ABIN1742212

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Rab3c in WB, IP und ICC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh) und Affe und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für Rab3c Antikörper (AA 154-227) (ABIN1742212)

Target: Rab3c (RAB3C, Member RAS Oncogene Family (Rab3c))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Rab3c Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Produktdetails anti-Rab3c Antikörper

Bindungsspezifität: AA 154-227

Spezifität: Specific for Rab 3c.

Aufreinigung: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Recombinant protein of human Rab 3c (aa 154-227).

Anwendungsinformationen

Applikationshinweise: WB: 1 : 1000 (AP staining)
ICC: 1 : 500
IHC: not tested yet

Kommentare:

This antibody has been affinity purified with a peptide consisting only of the Rab 3c specific epitope NTRLKETPPPPQPN (aa 211 - 224) of the human protein.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handhabung: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Lagerung: -20 °C

Informationen zur Lagerung: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

Referenzen für anti-Rab3c Antikörper (ABIN1742212)

Nishioka, Tooi, Isobe, Nakatsuji, Aiba: "BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer's disease models." in: Scientific reports, Vol. 6, pp. 33427, (2016) (PubMed).

Pavlos, Grønborg, Riedel, Chua, Boyken, Kloepper, Urlaub, Rizzoli, Jahn: "Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 40, pp. 13441-53, (2010) (PubMed).

Cai, Reim, Varoqueaux, Tapechum, Hill, Sørensen, Brose, Chow: "Complexin II plays a positive role in Ca2+-triggered exocytosis by facilitating vesicle priming." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 49, pp. 19538-43, (2008) (PubMed).

Details zu Rab3c

Target: Rab3c (RAB3C, Member RAS Oncogene Family (Rab3c))

Andere Bezeichnung: Rab 3c