RAB3A Antikörper (AA 154-227)

Produktnummer ABIN1742210

Der Kaninchen Polyklonal Anti-RAB3A Antikörper wurde für WB, IHC und ICC validiert. Er ist geeignet, RAB3A in Proben von Human, Ratte und Maus zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für RAB3A Antikörper (AA 154-227) (ABIN1742210)

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Produktdetails anti-RAB3A Antikörper

Bindungsspezifität: AA 154-227

Verwendungszweck: Rabbit anti-Rab3 antibody

Spezifität: Specific for all four Rab 3 isoforms a, b, c, d.

Kreuzreaktivität (Details): Reacts with: human (P20336, P20337, Q96E17, O95716), rat (P63012, Q63941, P62824, Q63942), mouse (P63011, Q9CZT8, P62823, P35276). Other species not tested yet.

Aufreinigung: affinity purified

Immunogen: Recombinant protein corresponding to AA 154 to 227 from human Rab3c (UniProt Id: Q96E17)

Anwendungsinformationen

Applikationshinweise: WB:1 : 1000 , IP:not tested yet ICC:1 : 1000, IHC:1 : 200 up to 1 : 500, IHC-P:not tested yet

Kommentare:

This antibody has been affinity purified with the complete antigen (aa 154 - 227) and recognizes all isoforms, due to the homology of Rab 3 proteins.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin was added for stabilization.

Handhabung: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Lagerung: -20 °C,-80 °C,4 °C

Informationen zur Lagerung: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin was added for stabilization. Do not freeze!

Referenzen für anti-RAB3A Antikörper (ABIN1742210)

Romanov, Alpár, Zhang, Zeisel, Calas, Landry, Fuszard, Shirran, Schnell, Dobolyi, Oláh, Spence, Mulder, Martens, Palkovits, Uhlen, Sitte, Botting, Wagner, Linnarsson, Hökfelt, Harkany: "A secretagogin locus of the mammalian hypothalamus controls stress hormone release." in: The EMBO journal, Vol. 34, Issue 1, pp. 36-54, (2015) (PubMed).

Spangler, Schmitz, Kevenaar, de Graaff, de Wit, Demmers, Toonen, Hoogenraad: "Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission." in: The Journal of cell biology, Vol. 201, Issue 6, pp. 915-28, (2013) (PubMed).

de Wit, Walter, Milosevic, Gulyás-Kovács, Riedel, Sørensen, Verhage: "Synaptotagmin-1 docks secretory vesicles to syntaxin-1/SNAP-25 acceptor complexes." in: Cell, Vol. 138, Issue 5, pp. 935-46, (2009) (PubMed).

Details zu RAB3A

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Andere Bezeichnung: Rab3

Hintergrund:

Synonyms: Ras-related protein 3C, Ras-related protein 3B, Rab 3a, Rab 3b, Rab 3c

Antigen Information: Rab3 proteins are the major Rab isoforms in brain and are highly enriched on synaptic vesicles

UniProt: Q96E17

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport