Neuroligin 3 Antikörper (AA 730-848)

Produktnummer ABIN1741449

Dieses Anti-Neuroligin 3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Neuroligin 3 in WB, IHC, ICC und IF. Geeignet für Ratte.

Kurzübersicht für Neuroligin 3 Antikörper (AA 730-848) (ABIN1741449)

Target: Neuroligin 3 (NLGN3)

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Neuroligin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: S110-29

Produktdetails anti-Neuroligin 3 Antikörper

Bindungsspezifität: AA 730-848

Spezifität: Detects ~110 kDa. Does not cross-react with Neuroligin-1, -2, -4 or -4.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3. Mouse: 99% identity (118/119 amino acids identical). Human: 98% identity (116/119 amino acids identical) ~60% identity with Neuroligin-1. ~40% identity with Neuroligin-2.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN1741449 was sufficient for detection of Neuroligin 3 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu Neuroligin 3

Target: Neuroligin 3 (NLGN3)

Andere Bezeichnung: Neuroligin 3

Hintergrund: Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses.

Gen-ID: 171297

UniProt: Q62889

Pathways: Synaptic Membrane