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VDAC1 Antikörper (AA 1-283) (Atto 390)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch VDAC1 in WB, IHC, IF und ICC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN1741216

Kurzübersicht für VDAC1 Antikörper (AA 1-283) (Atto 390) (ABIN1741216)

Target

Alle VDAC1 Antikörper anzeigen
VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

Reaktivität

  • 87
  • 43
  • 31
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 73
  • 26
  • 2
Maus

Klonalität

  • 62
  • 39
Monoklonal

Konjugat

  • 61
  • 6
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser VDAC1 Antikörper ist konjugiert mit Atto 390

Applikation

  • 87
  • 53
  • 40
  • 21
  • 18
  • 13
  • 13
  • 9
  • 7
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon

S152B-23
  • Bindungsspezifität

    • 15
    • 12
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-283

    Spezifität

    Detects ~30 kDa. Does not cross-react with VDAC2 or VDAC3 (based on KO validation results).

    Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Protein G Purified

    Immunogen

    Fusion protein amino acids 1-283 (full-length) of human VDAC1. Mouse: 98% identity (279/283 amino acids identical). Rat: 98% identity (279/283 amino acids identical) >60% identity with VDAC2 and VDAC3.

    Isotyp

    IgG2a
  • Applikationshinweise

    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.

    Kommentare

    1 μg/ml of ABIN1741216 was sufficient for detection of VDAC1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Conjugated antibodies should be stored at 4°C
  • Target

    VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

    Andere Bezeichnung

    VDAC1

    Hintergrund

    Voltage-dependent anion-selective channel protein 1 (also known as VDAC, VDAC1 or outer mitochondrial membrane protein porin 1) is the the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis.

    Gen-ID

    7416

    UniProt

    P21796
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