PARK7/DJ1 Antikörper (N-Term)

Produktnummer ABIN1737863

Produktdetails anti-PARK7/DJ1 Antikörper

Target: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Bindungsspezifität: AA 167-189, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARK7/DJ1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Reacts with human and mouse PARK7. Sequence homology to mouse and rat DJ-1 is 82 % .

Aufreinigung: Purified

Immunogen: Synthetic peptide corresponding to amino acids 167-189 (AIVEALNGKEVAAQVKAPLVLKD) of human PARK7 conjugated to KLH at the N-terminus.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB1:500

Positive control: HEK293 cell lysate or mouse brain tissue lysate

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4,

Handhabung: Dilute in PBS or medium which is identical to that used in the assay system.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

Haltbarkeit: 6 months

Details zu PARK7/DJ1

Target: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Andere Bezeichnung: Park7 (PARK7 Produkte)

Synonyme: DJ-1 antikoerper, DJ1 antikoerper, CAP1 antikoerper, Dj1 antikoerper, SP22 antikoerper, dj1 antikoerper, zgc:103725 antikoerper, park7b antikoerper, park7 antikoerper, park7a antikoerper, Parkinsonism associated deglycase antikoerper, Parkinson disease (autosomal recessive, early onset) 7 antikoerper, parkinson protein 7 antikoerper, parkinson protein 7 S homeolog antikoerper, parkinson protein 7 L homeolog antikoerper, PARK7 antikoerper, Park7 antikoerper, park7 antikoerper, park7.S antikoerper, park7.L antikoerper

Hintergrund: Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.

Protein DJ-1 Oncogene DJ1 Parkinson disease protein 7 Gene name: PARK7

Gen-ID: 11315

UniProt: Q99497

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport