GPER Antikörper (AA 357-370)

Produktnummer ABIN1735055

Produktdetails anti-GPER Antikörper

Target: GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))

Bindungsspezifität: AA 357-370

Reaktivität: Human, Hund, Affe

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GPER Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Reacts with GPR30 from human, gorilla, monkey and dogs

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): Predicted to cross reacts withmouse and rat protein (93 % immunogen sequences identity).

Aufreinigung: Antigen affinity purified

Immunogen: Synthetic peptide C-KAVIPDSTEQSDVR from positions 357-370 of human GPER (NP_001496.1). Percent identity with other species by BLAST analysis: Human, Monkey, Dog (100%), Mouse, Rat (93%)

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (3.75 - 7.5 μg/mL)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Minimize freezing and thawing.

Details zu GPER

Target: GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))

Andere Bezeichnung: GPR30 (GPER Produkte)

Hintergrund: Involved in various biological pathways like immunity, apoptosis, cell cycle or differentiation, GPR30 is the eostradiol receptor for ER2

Gen-ID: 2852

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process