Breast Carcinoma Amplified Sequence 1 (BCAS1), also known as Novel Amplified in Breast Cancer 1 (NABC1) was isolated from a region at 20q13 and is amplified in several tumor types. It is associated with more aggressive tumor phenotypes. BCAS1/NABC1 is highly expressed in some, but not all, breast cancer cell lines and in some breast tumors at 20q13.2. The BCAS1/NABC1 gene is predicted to encode a protein of 584 amino acids with no significant homology to other proteins.
Breast carcinoma-amplified sequence 1 Amplified and overexpressed in breast cancer Novel amplified in breast cancer 1 Gene name: BCAS1, AIBC1, NABC1