Amyloid Fibrils Antikörper

Produktnummer ABIN1731752

Produktdetails

Target: Amyloid Fibrils

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Dot Blot (DB)

Spezifität: Reacts withepitopes common to many human amyloid fibrils and fibrillar oligomers but not prefibrillar oligomers or natively folded proteins. Predicted to recognize mouse and rat based on sequence homology.

Aufreinigung: Purified

Immunogen: Fibrils prepared from human Abeta42 peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB1 -2 μg/mL DB0.5 - 1 μg/mL IHC1 -5 μg/mL ELISA1 - 10 μg/mL with amyloid fibril-containing samples on the solid phase.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS pH 7.0, 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute in PBS or medium which is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: This product is stable for at least 1 year at -20°C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.

Antigendetails

Target: Amyloid Fibrils

Hintergrund: Amyloid monomeric proteins can oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibers.