beta-2 Microglobulin Antikörper (AA 21-100)
Kurzübersicht für beta-2 Microglobulin Antikörper (AA 21-100) (ABIN1724930)
Target
Alle beta-2 Microglobulin (B2M) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 21-100
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Verwendungszweck
- B2M Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human B2M (AA: 21-100) expressed in E. Coli.
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Isotyp
- IgG2a
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Implication of the ?2-microglobulin gene in the generation of tumor escape phenotypes." in: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 9, pp. 1359-71, (2012) (PubMed).
: "Increased serum ?2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus patients." in: Lupus, Vol. 21, Issue 10, pp. 1098-104, (2012) (PubMed).
: "
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Implication of the ?2-microglobulin gene in the generation of tumor escape phenotypes." in: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 9, pp. 1359-71, (2012) (PubMed).
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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Andere Bezeichnung
- B2M
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Hintergrund
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This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
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Molekulargewicht
- 13.7 kDa
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Gen-ID
- 567
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UniProt
- P61769
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Pathways
- T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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